Publications
Cross-Vendor Validation of Proton Density Fat Fraction and T1 Mapping Using a Combined Proton Density Fat Fraction-T1 Phantom.
Starekova J, Weingärtner S, Rutkowski DR, Fullerton GC, Bae WC, Do HP, Madhuranthakam AJ, Malis V, Lin SQ, Serai SD, Yokoo T, Reeder SB, Brittain JH, Hernando D. Published in J Magn Reson Imaging. 2025 Sep;62(3):800-811. doi: 10.1002/jmri.29775. Epub 2025 Apr 18. PMID: 40251801; PMCID: PMC12335339.
Multi-Center, Multi-Vendor Validation of Simultaneous MRI-Based Proton Density Fat Fraction and R2* Mapping Using a Combined Proton Density Fat Fraction-R2* Phantom.
Starekova J, Rutkowski D, Bae WC, Do H, Madhuranthakam AJ, Malis V, Lin SQ, Serai S, Yokoo T, Reeder SB, Brittain JH, Hernando D. Published in J Magn Reson Imaging. 2025 Sep;62(3):800-811. doi: 10.1002/jmri.29775. Epub 2025 Apr 18. PMID: 40251801; PMCID: PMC12335339.
Linearity and bias of proton density fat fraction across the full dynamic range of 0–100%: a multiplatform, multivendor phantom study using 1.5T and 3T MRI at two sites.
Hu, H.H., Chen, H.SM. & Hernando, D. Published in Magn Reson Mater Phy. Jan 5 2024. DOI:10.1007/s10334-024-01148-9
Linearity and Bias of Proton Density Fat Fraction as a Quantitative Imaging Biomarker: A Multicenter, Multiplatform, Multivendor Phantom Study
Hu H, Yokoo T, et al. Published in Radiology. Jan 19 2021. DOI: 10.1148/radiol.2021202912
Temperature-corrected proton density fat fraction estimation using chemical shift-encoded MRI in phantoms
Navaratna R, et al. Published in Magnetic Resonance in Medicine. Feb 9 2021. DOI: 10.1002/mrm.28669
Design and evaluation of quantitative MRI phantoms to mimic the simultaneous presence of fat, iron, and fibrosis in the liver.
Zhao R, Hamilton G, Brittain JH, Reeder SB, Hernando D. Magn Reson Med. 2021 Feb;85(2):734-747. doi: 10.1002/mrm.28452.
Conference
Abstracts
Multi-Modality Quantitative Fat Phantom for MRI and CT Measurements of Myosteatosis.
David R Rutkowski, Jeff Kammerman, José Guerrero, Aria M Salyapongse, Adam Kuchnia, Timothy P Szczykutowicz, Diego Hernando, Scott B Reeder, Jean H Brittain. International Society for Magnetic Resonance in Medicine Annual Meeting. Cape Town, South Africa. May 9-14, 2026.
Multi-Modality Quantitative Fat Phantom for MRI and CT Measurements of Steatotic Liver Disease.
David R Rutkowski, Jeff Kammerman, José Guerrero, Robert Moskwa, Ke Li, Timothy P Szczykutowicz, Scott B Reeder, Diego Hernando, Jean H Brittain. International Society for Magnetic Resonance in Medicine Annual Meeting. Honolulu, HI, USA. May 10-15, 2025.
Combined Quantitative Fat and Stiffness Phantom for Simultaneous CSE-MRI and MRE Quality Assurance of Steatotic Liver Disease.
Rutkowski DR, do Vale Souza R, Guerrero-Gonzalez J, Kammerman J, Moskwa R, Urban MW, Rossman PJ, Pepin K, Heilman J, Hernando D, Reeder SB, Brittain JH. International Society for Magnetic Resonance in Medicine Annual Meeting. Honolulu, HI, USA. May 10-15, 2025.
Muli-center, multi-vendor validation of PDFF-R2* mapping in an optimized fat-iron phantom.
Starekova J, Rutkowski D, Bae W, Do H, Madhuranthakam A, Malis V, Mukherjee S, Qin Lin S, Serai S, Yokoo T, Reeder S, Brittain J, Hernando D. International society for magnetic resonance in medicine. 2023. Toronto, ON, Canada. Summa Cum Laude Merit Award.
Combined Stiffness and PDFF Phantom for Quality Assurance of Quantitative Magnetic Resonance Elastography and Fat Fraction Imaging.
Rutkowski DR, Roldán-Alzate A, Guerrero-González J, Hernando D, Reeder SB, Brittain JH. International Society for Magnetic Resonance in Medicine 2022.
Multi-Site, Multi-Vendor, and Multi-Platform Assessment of Accuracy of Quantitative Proton-Density Fat Fraction (PDFF) at 1.5T and 3T with a Standardized Spherical Phantom: Results from a Study by the RSNA QIBA PDFF Committee.
Hu H, et al. Radiological Society of North America Annual Meeting, Abstract SSA22-03. Chicago, IL, December 1, 2019.
Hu H, et al. International Society for Magnetic Resonance in Medicine Annual Meeting, abstract 1023. Montreal, Canada. May 16, 2019.
Grants
Awarded
SBIR Advance Phase 2 (2026)
NIST SBIR Phase 2 (2025)
NIST SBIR Phase 1 (2024)
SBIR Advance Phase 1 (2023)
STTR Phase 1 (2023)
SBIR Advance Phase 2 (2019)
SBIR Phase 2 (2019)
SBIR Advance Phase 1 (2018)
STTR Phase 1 (2018)
Produced under a grant from the University of Wisconsin-System SBIR Advance Matching Grant Fund through its partnership with the Wisconsin Economic Development Corporation.